Minoxidil for Men
If you’re dealing with hereditary hair loss, you’ve probably heard about Dr Bonaros prescribing minoxidil for men.
The topical minoxidil solution is available in various consistencies, but the oral form used off-label has become more popular.
Explore more details about using minoxidil for male pattern baldness and information on its different formulations and potential side effects.
Reviewed by Dr Epameinondas Bonaros
Table of Contents
Overview of Minoxidil
Minoxidil, initially a medication for high blood pressure, is widely used as a hair loss treatment. Topical formulations were developed in the late 1980s to address male pattern baldness (androgenetic alopecia).
The treatment’s success eventually led to its approval for women experiencing hereditary hair loss. The medicine is also sold under the trademark Regaine® (known as Rogaine in the US).
Consult your doctor before using this medication if you have a heart disease (such as abnormal rhythms, angina, or chest pain) or circulation disorders.
Below, we examine how the medication functions in the body and assess its efficacy in treating hair loss and regrowing hair.
How Minoxidil Works
When taken for hair recovery, minoxidil targets follicles directly, working beneath the scalp’s surface. The medication enhances follicular function and vitality; in other words, it reinforces weakened hair follicles in treated regions.
Extending the active growth period of the hair cycle helps combat progressive hair thinning and encourages new growth. In addition, stimulating dormant follicles can also help revitalise growth in areas experiencing hair loss.
Mechanism of Action
As an active ingredient, minoxidil works primarily by dilating blood vessels in the scalp, though scientists are still studying its complete mechanism of action. This vasodilation increases blood flow to hair follicles, delivering vital oxygen and nutrients that stimulate hair growth.
Available Forms
As part of a treatment for male or female pattern hair loss doctors prescribe minoxidil pills for men or topical formulations, including foam, scalp liquid solution and shampoo.
Efficacy of Minoxidil
Minoxidil for men’s hair loss and regrowth is scientifically proven to be very effective.
Clinical Evidence: Clinical studies have demonstrated that when used as directed, the medicine helps combat progressive hair loss and promotes hair regrowth in patients with androgenetic alopecia. Research measurements have documented increases in the number of visible hairs and their thickness in treated areas.
Response Variability: Patients who begin using the medication at the first signs of baldness or a receding hairline generally see better outcomes than those who start treatment in advanced stages.
Timeframe for Results: On the topical medication, many patients tend to show initial signs of improvement between months two and four of treatment. Optimal results generally develop gradually over approximately 12 months of continued use. For oral tablet patients, noticeable hair regrowth usually happens within 6-12 months.
Note: Following your doctor’s application or dosage instructions is key to achieving the best possible results.
Doctors do not recommend it for patients with a painful scalp, sudden or patchy hair loss, or no family history of hair loss.
Minoxidil for Male Hair Loss
Minoxidil has been a trusted and clinically proven hair restoration plan for men for decades.
While the topical solution is frequently used, oral capsules have gained attention as an alternative option.
Minoxidil Results for Men
Various clinical trials have proven minoxidil’s effectiveness in treating men’s hair loss.
High Success Rate: A randomised Chinese study reported a 42.3% success rate with 5% foam after six months of twice-daily use. Other research reports success rates of 35% and 67.7%, respectively.
Comparing Hair Therapy Options: A 12-month double-blind trial found that low-dose oral minoxidil (LDOM) (5 mg daily) is as effective as a 5% topical formulation for men with androgenetic alopecia. LDOM offers an option for patients who prefer oral therapy or are allergic to topical treatments.
Combination Treatment Benefits: A 2021 study of 69 men with androgenetic alopecia indicates that using platelet-rich plasma and minoxidil together may enhance their individual effects. This combined treatment approach has shown success in addressing androgenetic alopecia.
Note: Male pattern hair loss is progressive, so continued use of the medication is necessary to maintain results. Once you stop treatment, hair thinning will resume as before.
Minoxidil Side Effects for Men
Before you begin your hair growth plan, here are general side effects and specific adverse symptoms from the different formulations. Please note that symptoms vary, and you should thoroughly discuss them with your prescribing doctor.
- Excess unwanted hair growth (hypertrichosis) on the face, arms and other parts of the body
- Initial hair shedding
Topical Minoxidil
- Irritated scalp
- Irritated skin
- Itchy allergic reaction
- Rare adverse effects include increased heartbeat, chest pain, dizziness, difficulty breathing and sudden weight gain.
- Skin redness
Oral Minoxidil
- Leg swelling (oedema)
- Low blood pressure and dizziness
- Rapid heart rate (tachycardia)
- Other side effects: Heart palpitations, tiredness, and general dizziness
Topical vs Oral Minoxidil for Men's Hair Loss
Choosing between oral and topical solutions? Here’s what you need to consider: If you’re someone who struggles to maintain a twice-daily routine, oral tablets might be your better option. On the other hand, if you prefer targeted treatment and don’t mind the application process, the topical solution could be perfect for you.
Learn more about the features and benefits of topical and oral minoxidil to stimulate hair growth in men.
Oral Minoxidil for Men
Many hair regrowth specialists prefer low-dose oral minoxidil (LDOM) due to its ease of use and proven efficiency. The recommended dose for men ranges from 1.25 to 5 mg a day.
A multicenter study of 1404 male and female patients found that LDOM overwhelmingly has an excellent safety profile for treating hair loss.
LDOM is a good option for male patients who don’t respond well to topical applications. The topical solution is not consistently absorbed, even in a foam formulation. As a prodrug, it requires conversion at the follicle level to become active.
Some patients may lack the enzyme needed to convert the solution into minoxidil sulphate, a limitation that does not affect LDOM.
Topical Minoxidil for Men
Topical minoxidil is available in liquid and foam formulations and is applied directly to the hair loss area. For men, the recommended dosage to promote hair regrowth is twice daily. Apply the solution to dry hair and scalp.
The innovation of foam improved the delivery of the active ingredient to the target area. It allows for better absorption and reduces scalp irritation compared to liquid. Under the brand name Regaine, the product is marketed as an Extra-Strong Scalp Foam.
Although the topical solution effectively treats hair loss, many patients struggle with compliance due to the twice-daily application and scalp irritation.
For comprehensive medical help for hair loss, including missed doses catch-up and extra strength options, email info@drbonaros.com.
Dr Bonaros: Excellence in Hair Restoration, Guided by Empathy
At the Dr Bonaros hair clinic for men and women, we have created a comfortable, judgment-free environment where you can explore your hair regrowth treatment options.
Dr Bonaros brings the highest level of accredited expertise. He is a member of the British Association of Hair Restoration Surgery (BAHRS) and Scotland’s only member of the International Society of Hair Restoration Surgery (ISHRS).
Whether you’re experiencing hereditary hair loss or gradual thinning hair, our proven expertise and guidance can help you regrow your hair and confidence.
Dr Bonaros can provide a prescription for minoxidil for men experiencing hair loss and thinning. Schedule your consultation now to determine if minoxidil is your optimal hair restoration plan.
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